I think I've tried all the creams and serums against wrinkles as well, and nothing helped at all. I think that you should check this page
https://www.dermalrepaircomplexbhmd.com/reviews and read the reviews about the supplement that I use right now. It's pretty good, and I'm sure that you will see the result in no time. This supplement made my skin much more smooth and bright, so you need to consider using it.