I currently have 1200 hours in the game and I've tried all combination of weapon. First of all, when wearing heavy armor, you can't expect to go one on one against a naked and catch up to him. You will most likely die due to your lack of speed. Armored people need to fight in units with ranged support. Use naphta grenades, two handed weapon(Maul, bardiche, broad axe, glaive). These are by far the best. I've done my fair share of naked fighting and I can say that my current setup is now, (60 throw, 30 leather // 60 two S, 60 plate, 60 two axe, 60 two blunt, 60 war cry // 60 militia, 60 padded, 90 spear on a 600 skill cap) Light leather with half plate helmet, Broad axe, Long pike, War cries.
This is, by far, more effective than naked combat. 60 str, 50 agi, 10 int, 10 con, 20 will.
Don't get me wrong, naked combat is really good because it's forgiving, you can miss a swing and run. When you're armoured up, it's all about coordination and timing.